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Two tagging single‐nucleotide polymorphisms to capture HLA‐DRB1*07:01–DQA1*02:01–DQB1*02:02 haplotype associated with asparaginase hypersensitivity
AIMS: Asparaginase (ASP) hypersensitivity is a well‐known challenge in the treatment of lymphoblastic malignancies. In terms of cost considerations, the cheap native Escherichia coli ASP, the most immunogenic form of this medication, is used in the first line in middle‐income countries. Previously,...
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| Pubblicato in: | Br J Clin Pharmacol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8247313/ https://ncbi.nlm.nih.gov/pubmed/33217039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14664 |
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