HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression

The HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 haplotype is linked to protection from the development of type 1 diabetes (T1D). However, it is not known at which stages in the natural history of T1D development this haplotype affords protection. We examined a cohort of 3,358 autoantibody-positive relative...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Diabetes
Prif Awduron: Pugliese, Alberto, Boulware, David, Yu, Liping, Babu, Sunanda, Steck, Andrea K., Becker, Dorothy, Rodriguez, Henry, DiMeglio, Linda, Evans-Molina, Carmella, Harrison, Leonard C., Schatz, Desmond, Palmer, Jerry P., Greenbaum, Carla, Eisenbarth, George S., Sosenko, Jay M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2016
Pynciau:
Genetics/Genomes/Proteomics/Metabolomics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806662/
https://ncbi.nlm.nih.gov/pubmed/26822082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1105
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