Two tagging single‐nucleotide polymorphisms to capture HLA‐DRB1*07:01–DQA1*02:01–DQB1*02:02 haplotype associated with asparaginase hypersensitivity

AIMS: Asparaginase (ASP) hypersensitivity is a well‐known challenge in the treatment of lymphoblastic malignancies. In terms of cost considerations, the cheap native Escherichia coli ASP, the most immunogenic form of this medication, is used in the first line in middle‐income countries. Previously,...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Kutszegi, Nóra, Gézsi, András, F. Semsei, Ágnes, Müller, Judit, Simon, Réka, Kovács, Erika Rozália, Hegedüs, Katalin, Kovács, Gábor T., Szalai, Csaba, Erdélyi, Dániel J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247313/
https://ncbi.nlm.nih.gov/pubmed/33217039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14664
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