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Association between the HLA-DRB1*03:01-DQB1*02:01 haplotype and PF4/heparin antibodies

HLA-DRB1*03:01-DQB1*02:01 haplotype patients develop higher anti–platelet factor 4/heparin (PF4/H) levels following IV heparin exposure. HLA-restricted antigen presentation may play a role in the formation of anti-PF4/H antibodies.

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Zhang, Ray, Duffy, Brian F., Lange, Vinzenz, Eby, Charles S., Liu, Chang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849947/
https://ncbi.nlm.nih.gov/pubmed/31648318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000311
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