Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis

Cellular stress can lead to several human disease pathologies due to aberrant cell death. The p53 family (tp53, tp63, and tp73) and downstream transcriptional apoptotic target genes (PUMA/BBC3 and NOXA/PMAIP1) have been implicated as mediators of stress signals. To evaluate the importance of key str...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Wang, Jun, Thomas, Holly R., Li, Zhang, Yeo, Nan Cher (Florence), Scott, Hannah E., Dang, Nghi, Hossain, Mohammed Iqbal, Andrabi, Shaida A., Parant, John M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245518/
https://ncbi.nlm.nih.gov/pubmed/34193827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03902-6
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