Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways

The activation of tumor suppressor p53 induces apoptosis or cell cycle arrest depending on the state and type of cell, but it is not fully understood how these different responses are regulated. Here, we show that Puma and Noxa, the well-known p53-inducible proapoptotic members of the Bcl-2 family,...

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Bibliografiske detaljer
Main Authors: Shibue, Tsukasa, Suzuki, Saori, Okamoto, Hideaki, Yoshida, Hiroki, Ohba, Yusuke, Takaoka, Akinori, Taniguchi, Tadatsugu
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618103/
https://ncbi.nlm.nih.gov/pubmed/17024184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601359
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