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Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways

The activation of tumor suppressor p53 induces apoptosis or cell cycle arrest depending on the state and type of cell, but it is not fully understood how these different responses are regulated. Here, we show that Puma and Noxa, the well-known p53-inducible proapoptotic members of the Bcl-2 family,...

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Hlavní autoři: Shibue, Tsukasa, Suzuki, Saori, Okamoto, Hideaki, Yoshida, Hiroki, Ohba, Yusuke, Takaoka, Akinori, Taniguchi, Tadatsugu
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618103/
https://ncbi.nlm.nih.gov/pubmed/17024184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601359
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