Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis

Cellular stress can lead to several human disease pathologies due to aberrant cell death. The p53 family (tp53, tp63, and tp73) and downstream transcriptional apoptotic target genes (PUMA/BBC3 and NOXA/PMAIP1) have been implicated as mediators of stress signals. To evaluate the importance of key str...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Jun, Thomas, Holly R., Li, Zhang, Yeo, Nan Cher (Florence), Scott, Hannah E., Dang, Nghi, Hossain, Mohammed Iqbal, Andrabi, Shaida A., Parant, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245518/
https://ncbi.nlm.nih.gov/pubmed/34193827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03902-6
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