Integral role of Noxa in p53-mediated apoptotic response

The tumor suppressor p53 exerts its versatile function to maintain the genomic integrity of a cell, and the life of cancerous cells with DNA damage is often terminated by induction of apoptosis. We studied the role of Noxa, one of the transcriptional targets of p53 that encodes a proapoptotic protei...

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Detalhes bibliográficos
Main Authors: Shibue, Tsukasa, Takeda, Kiyoshi, Oda, Eri, Tanaka, Hiroshi, Murasawa, Hideki, Takaoka, Akinori, Morishita, Yasuyuki, Akira, Shizuo, Taniguchi, Tadatsugu, Tanaka, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196460/
https://ncbi.nlm.nih.gov/pubmed/12952892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1103603
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