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Integral role of Noxa in p53-mediated apoptotic response

The tumor suppressor p53 exerts its versatile function to maintain the genomic integrity of a cell, and the life of cancerous cells with DNA damage is often terminated by induction of apoptosis. We studied the role of Noxa, one of the transcriptional targets of p53 that encodes a proapoptotic protei...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Shibue, Tsukasa, Takeda, Kiyoshi, Oda, Eri, Tanaka, Hiroshi, Murasawa, Hideki, Takaoka, Akinori, Morishita, Yasuyuki, Akira, Shizuo, Taniguchi, Tadatsugu, Tanaka, Nobuyuki
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196460/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12952892/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1103603
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