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Targeting the apoptotic Mcl-1-PUMA interface with a dual-acting compound
Despite intensive efforts in the search for small molecules with anti-cancer activity, it remains challenging to achieve both high effectiveness and safety, since many agents lack the selectivity to only act on cancer cells. The interface of two apoptotic proteins, myeloid cell leukemia-1 (Mcl-1) an...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589576/ https://ncbi.nlm.nih.gov/pubmed/28903337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17294 |
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