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PUMA mediates the apoptotic response to p53 in colorectal cancer cells
Although several genes that might mediate p53-induced apoptosis have been proposed, none have previously been shown to play an essential role in this process through a rigorous gene disruption approach. We used a gene-targeting approach to evaluate p53-mediated death in human colorectal cancer cells...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149936/ https://ncbi.nlm.nih.gov/pubmed/12574499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2627984100 |
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