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PUMA mediates the apoptotic response to p53 in colorectal cancer cells

Although several genes that might mediate p53-induced apoptosis have been proposed, none have previously been shown to play an essential role in this process through a rigorous gene disruption approach. We used a gene-targeting approach to evaluate p53-mediated death in human colorectal cancer cells...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Yu, Jian, Wang, Zhenghe, Kinzler, Kenneth W., Vogelstein, Bert, Zhang, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149936/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574499/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2627984100
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