PUMA mediates the apoptotic response to p53 in colorectal cancer cells
Although several genes that might mediate p53-induced apoptosis have been proposed, none have previously been shown to play an essential role in this process through a rigorous gene disruption approach. We used a gene-targeting approach to evaluate p53-mediated death in human colorectal cancer cells...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149936/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2627984100 |
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