PUMA mediates the apoptotic response to p53 in colorectal cancer cells

Although several genes that might mediate p53-induced apoptosis have been proposed, none have previously been shown to play an essential role in this process through a rigorous gene disruption approach. We used a gene-targeting approach to evaluate p53-mediated death in human colorectal cancer cells...

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Detaylı Bibliyografya
Asıl Yazarlar: Yu, Jian, Wang, Zhenghe, Kinzler, Kenneth W., Vogelstein, Bert, Zhang, Lin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC149936/
https://ncbi.nlm.nih.gov/pubmed/12574499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2627984100
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