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Assessing vaccine durability in randomized trials following placebo crossover

Randomized vaccine trials are used to assess vaccine efficacy (VE) and to characterize the durability of vaccine‐induced protection. If efficacy is demonstrated, the treatment of placebo volunteers becomes an issue. For COVID‐19 vaccine trials, there is broad consensus that placebo volunteers should...

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Detalles Bibliográficos
Publicado en:Stat Med
Main Authors: Fintzi, Jonathan, Follmann, Dean
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8242890/
https://ncbi.nlm.nih.gov/pubmed/33928660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.9001
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