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Assessing vaccine durability in randomized trials following placebo crossover

Randomized vaccine trials are used to assess vaccine efficacy (VE) and to characterize the durability of vaccine‐induced protection. If efficacy is demonstrated, the treatment of placebo volunteers becomes an issue. For COVID‐19 vaccine trials, there is broad consensus that placebo volunteers should...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Fintzi, Jonathan, Follmann, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8242890/
https://ncbi.nlm.nih.gov/pubmed/33928660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.9001
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