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Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes

Cationic liposomes can be intravenously injected to deliver short interfering (si)RNAs into the lungs. The present study investigated the effects of sterol derivatives in systemically injected siRNA/cationic liposome complexes (siRNA lipoplexes) on gene-knockdown in the lungs of mice. Cationic lipos...

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Détails bibliographiques
Publié dans:Mol Med Rep
Auteurs principaux: Hattori, Yoshiyuki, Saito, Hiromu, Oku, Teruaki, Ozaki, Kei-Ichi
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240178/
https://ncbi.nlm.nih.gov/pubmed/34165169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12237
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