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Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes

Cationic liposomes can be intravenously injected to deliver short interfering (si)RNAs into the lungs. The present study investigated the effects of sterol derivatives in systemically injected siRNA/cationic liposome complexes (siRNA lipoplexes) on gene-knockdown in the lungs of mice. Cationic lipos...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Hattori, Yoshiyuki, Saito, Hiromu, Oku, Teruaki, Ozaki, Kei-Ichi
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240178/
https://ncbi.nlm.nih.gov/pubmed/34165169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12237
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