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In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes

RNA interference (RNAi) is a powerful tool to treat diseases and elucidate target gene function. Prior to clinical implementation, however, challenges including the safe, efficient and targeted delivery of siRNA must be addressed. Here, we report cationic nanogel nanostructured polymers (NSPs) prepa...

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Détails bibliographiques
Publié dans:Bioengineering (Basel)
Auteurs principaux: Shrivats, Arun R., Mishina, Yuji, Averick, Saadyah, Matyjaszewski, Krzysztof, Hollinger, Jeffrey O.
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894740/
https://ncbi.nlm.nih.gov/pubmed/27280121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering2030160
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