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In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes

RNA interference (RNAi) is a powerful tool to treat diseases and elucidate target gene function. Prior to clinical implementation, however, challenges including the safe, efficient and targeted delivery of siRNA must be addressed. Here, we report cationic nanogel nanostructured polymers (NSPs) prepa...

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Detalhes bibliográficos
Publicado no:Bioengineering (Basel)
Main Authors: Shrivats, Arun R., Mishina, Yuji, Averick, Saadyah, Matyjaszewski, Krzysztof, Hollinger, Jeffrey O.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894740/
https://ncbi.nlm.nih.gov/pubmed/27280121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering2030160
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