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In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes

RNA interference (RNAi) is a powerful tool to treat diseases and elucidate target gene function. Prior to clinical implementation, however, challenges including the safe, efficient and targeted delivery of siRNA must be addressed. Here, we report cationic nanogel nanostructured polymers (NSPs) prepa...

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Bibliografiske detaljer
Udgivet i:Bioengineering (Basel)
Main Authors: Shrivats, Arun R., Mishina, Yuji, Averick, Saadyah, Matyjaszewski, Krzysztof, Hollinger, Jeffrey O.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894740/
https://ncbi.nlm.nih.gov/pubmed/27280121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering2030160
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