Nanogel-Mediated RNAi Against Runx2 and Osx Inhibits Osteogenic Differentiation in Constitutively Active BMPR1A Osteoblasts

Trauma-induced heterotopic ossification (HO) and fibrodysplasia ossificans progressiva (FOP) are acquired and genetic variants of pathological bone formation occurring in soft tissues. Conventional treatment modalities target the inflammatory processes preceding bone formation. We investigated the d...

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Publicat a:ACS Biomater Sci Eng
Autors principals: Shrivats, Arun R., McDermott, Michael C., Klimak, Molly, Averick, Saadyah E., Pan, Haichun, Matyjaszewski, Krzysztof, Mishina, Yuji, Hollinger, Jeffrey O.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790085/
https://ncbi.nlm.nih.gov/pubmed/26985455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.5b00294
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