Cationic Nanogel-mediated Runx2 and Osterix siRNA Delivery Decreases Mineralization in MC3T3 Cells

BACKGROUND: Heterotopic ossification (HO) may occur after musculoskeletal trauma, traumatic brain injury, and total joint arthroplasty. As such, HO is a compelling clinical concern in both military and civilian medicine. A possible etiology of HO involves dysregulated signals in the bone morphogenet...

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Detalhes bibliográficos
Publicado no:Clin Orthop Relat Res
Main Authors: Shrivats, Arun R., Hsu, Eric, Averick, Saadyah, Klimak, Molly, Watt, April C. S., DeMaio, Marlene, Matyjaszewski, Krzysztof, Hollinger, Jeffrey O.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418993/
https://ncbi.nlm.nih.gov/pubmed/25448327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-014-4073-0
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