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Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Prion diseases result from the misfolding of the normal, cellular prion protein (PrP(C)) to an abnormal protease resistant isomer called PrP(Res). The emergence of prion diseases in wildlife populations and their increasing threat to human health has led to increased efforts to find a treatment for...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Bender, Heather R., Kane, Sarah, Zabel, Mark D.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091666/
https://ncbi.nlm.nih.gov/pubmed/27501362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54106
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