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Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Prion diseases result from the misfolding of the normal, cellular prion protein (PrP(C)) to an abnormal protease resistant isomer called PrP(Res). The emergence of prion diseases in wildlife populations and their increasing threat to human health has led to increased efforts to find a treatment for...

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Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Bender, Heather R., Kane, Sarah, Zabel, Mark D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091666/
https://ncbi.nlm.nih.gov/pubmed/27501362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54106
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