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Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Prion diseases result from the misfolding of the normal, cellular prion protein (PrP(C)) to an abnormal protease resistant isomer called PrP(Res). The emergence of prion diseases in wildlife populations and their increasing threat to human health has led to increased efforts to find a treatment for...

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Bibliografske podrobnosti
izdano v:J Vis Exp
Main Authors: Bender, Heather R., Kane, Sarah, Zabel, Mark D.
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091666/
https://ncbi.nlm.nih.gov/pubmed/27501362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54106
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