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Comparative cellular pharmacokinetics and pharmacodynamics of siRNA delivery by SPANosomes and by cationic liposomes

Mechanistic understanding of intracellular trafficking is important for the development of small interfering RNA (siRNA) delivery vehicles. Here, we describe a novel methodology to quantitatively analyze nanocarrier-mediated disposition of siRNA. Cellular uptake and cytoplasmic release of siRNA over...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhou, Chenguang, Zhang, Yue, Yu, Bo, Phelps, Mitch A., Lee, L. James, Lee, Robert J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633702/
https://ncbi.nlm.nih.gov/pubmed/23117046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2012.10.002
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