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SPANosomes as delivery vehicles for small interfering RNA (siRNA)

Non-ionic surfactant vesicles, or SPANosomes (SPs), comprised of cationic lipid and sorbitan monooleate (Span 80) were synthesized and evaluated as siRNA vectors. The SPs had a mean diameter of less than 100 nm and exhibited excellent colloidal stability. The SP/siRNA complexes possessed a slightly...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Chenguang, Mao, Yicheng, Sugimoto, Yasuro, Zhang, Yue, Kanthamneni, Naveen, Yu, Bo, Brueggemeier, Robert W., Lee, L. James, Lee, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273546/
https://ncbi.nlm.nih.gov/pubmed/22149175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200426h
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