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Delivery of small-interfering RNA (siRNA) to the brain
BACKGROUND: Two fundamental difficulties in the delivery of drugs to treat central nervous system (CNS) diseases are the systemic delivery of therapeutics across the bloodbrain-barrier (BBB), and the targeting of drugs to specific tissues or cells within the brain. With the advent and promise of RNA...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698461/ https://ncbi.nlm.nih.gov/pubmed/19441914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543770802680195 |
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