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Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes

Cationic liposomes can be intravenously injected to deliver short interfering (si)RNAs into the lungs. The present study investigated the effects of sterol derivatives in systemically injected siRNA/cationic liposome complexes (siRNA lipoplexes) on gene-knockdown in the lungs of mice. Cationic lipos...

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Detalles Bibliográficos
Publicado en:Mol Med Rep
Main Authors: Hattori, Yoshiyuki, Saito, Hiromu, Oku, Teruaki, Ozaki, Kei-Ichi
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240178/
https://ncbi.nlm.nih.gov/pubmed/34165169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12237
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