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Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes

Cationic liposomes can be intravenously injected to deliver short interfering (si)RNAs into the lungs. The present study investigated the effects of sterol derivatives in systemically injected siRNA/cationic liposome complexes (siRNA lipoplexes) on gene-knockdown in the lungs of mice. Cationic lipos...

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Podrobná bibliografie
Vydáno v:Mol Med Rep
Hlavní autoři: Hattori, Yoshiyuki, Saito, Hiromu, Oku, Teruaki, Ozaki, Kei-Ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240178/
https://ncbi.nlm.nih.gov/pubmed/34165169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12237
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