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Fructose Causes Liver Damage, Polyploidy, and Dysplasia in the Setting of Short Telomeres and p53 Loss

Studies in humans and model systems have established an important role of short telomeres in predisposing to liver fibrosis through pathways that are incompletely understood. Recent studies have shown that telomere dysfunction impairs cellular metabolism, but whether and how these metabolic alterati...

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Detalhes bibliográficos
Publicado no:Metabolites
Main Authors: Chronowski, Christopher, Akhanov, Viktor, Chan, Doug, Catic, Andre, Finegold, Milton, Sahin, Ergün
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234056/
https://ncbi.nlm.nih.gov/pubmed/34204343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11060394
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