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Axis of ageing: telomeres, p53 and mitochondria
Progressive DNA damage and mitochondrial decline are both considered to be prime instigators of natural ageing. Traditionally, these two pathways have been viewed largely in isolation. However, recent studies have revealed a molecular circuit that directly links DNA damage to compromised mitochondri...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718675/ https://ncbi.nlm.nih.gov/pubmed/22588366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3352 |
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