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Beyond effector caspase inhibition: Bcl2L12 neutralizes p53 signaling in glioblastoma

Malignant gliomas are the most common and lethal primary central nervous system cancer. Glioblastoma mutliforme (GBM), the most aggressive of these neoplasms, are generally lethal within two years of diagnosis due in part to the intense apoptosis resistance of its cancer cells, hence poor therapeuti...

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Detalhes bibliográficos
Main Authors: Stegh, Alexander H, DePinho, Ronald A
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048071/
https://ncbi.nlm.nih.gov/pubmed/21200141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.1.14365
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