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Beyond effector caspase inhibition: Bcl2L12 neutralizes p53 signaling in glioblastoma
Malignant gliomas are the most common and lethal primary central nervous system cancer. Glioblastoma mutliforme (GBM), the most aggressive of these neoplasms, are generally lethal within two years of diagnosis due in part to the intense apoptosis resistance of its cancer cells, hence poor therapeuti...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048071/ https://ncbi.nlm.nih.gov/pubmed/21200141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.1.14365 |
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