Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma

Glioblastoma (GBM) is an astrocytic brain tumor characterized by an aggressive clinical course and intense resistance to all therapeutic modalities. Here, we report the identification and functional characterization of Bcl2L12 (Bcl2-like-12) that is robustly expressed in nearly all human primary GBM...

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Detalhes bibliográficos
Main Authors: Stegh, Alexander H., Kim, Hyunggee, Bachoo, Robert M., Forloney, Kristin L., Zhang, Jean, Schulze, Harald, Park, Kevin, Hannon, Gregory J., Yuan, Junying, Louis, David N., DePinho, Ronald A., Chin, Lynda
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1759904/
https://ncbi.nlm.nih.gov/pubmed/17210792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1480007
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