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Axis of ageing: telomeres, p53 and mitochondria

Progressive DNA damage and mitochondrial decline are both considered to be prime instigators of natural ageing. Traditionally, these two pathways have been viewed largely in isolation. However, recent studies have revealed a molecular circuit that directly links DNA damage to compromised mitochondri...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sahin, Ergün, DePinho, Ronald A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718675/
https://ncbi.nlm.nih.gov/pubmed/22588366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3352
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