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MRX-dependent DNA Damage Response to Short Telomeres

Telomere structure allows cells to distinguish the natural chromosome ends from double-strand breaks (DSBs). However, DNA damage response proteins are intimately involved in telomere metabolism, suggesting that functional telomeres may be recognized as DNA damage during a time window. Here we show b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Viscardi, Valeria, Bonetti, Diego, Cartagena-Lirola, Hugo, Lucchini, Giovanna, Longhese, Maria Pia
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949382/
https://ncbi.nlm.nih.gov/pubmed/17538011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0285
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