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Short Telomeres Induce a DNA Damage Response in Saccharomyces cerevisiae

Telomerase-deficient Saccharomyces cerevisiae cells show a progressive decrease in telomere length. When grown for several days in log phase, the tlc1Δ cells initially display wild-type growth kinetics with subsequent loss of growth potential after which survivors are generated via RAD52-dependent h...

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Bibliografiske detaljer
Main Authors: IJpma, Arne S., Greider, Carol W.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151574/
https://ncbi.nlm.nih.gov/pubmed/12631718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-04-0057
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