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Multi-Target Directed Ligands (MTDLs) Binding the σ(1) Receptor as Promising Therapeutics: State of the Art and Perspectives
The sigma-1 (σ(1)) receptor is a ‘pluripotent chaperone’ protein mainly expressed at the mitochondria–endoplasmic reticulum membrane interfaces where it interacts with several client proteins. This feature renders the σ(1) receptor an ideal target for the development of multifunctional ligands, whos...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8232171/ https://ncbi.nlm.nih.gov/pubmed/34198620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126359 |
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