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Multi-Target Directed Ligands (MTDLs) Binding the σ(1) Receptor as Promising Therapeutics: State of the Art and Perspectives
The sigma-1 (σ(1)) receptor is a ‘pluripotent chaperone’ protein mainly expressed at the mitochondria–endoplasmic reticulum membrane interfaces where it interacts with several client proteins. This feature renders the σ(1) receptor an ideal target for the development of multifunctional ligands, whos...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8232171/ https://ncbi.nlm.nih.gov/pubmed/34198620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126359 |
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