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MRP1-Collateral Sensitizers as a Novel Therapeutic Approach in Resistant Cancer Therapy: An In Vitro and In Vivo Study in Lung Resistant Tumor

Multidrug resistance (MDR) is the main obstacle to current chemotherapy and it is mainly due to the overexpression of some efflux transporters such as MRP1. One of the most studied strategies to overcome MDR has been the inhibition of MDR pumps through small molecules, but its translation into the c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Riganti, Chiara, Giampietro, Roberta, Kopecka, Joanna, Costamagna, Costanzo, Abatematteo, Francesca Serena, Contino, Marialessandra, Abate, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247425/
https://ncbi.nlm.nih.gov/pubmed/32397184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093333
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