Local Colonic Administration of a Serine Protease Inhibitor Improves Post-Inflammatory Visceral Hypersensitivity in Rats

Dysregulation of the protease–antiprotease balance in the gastrointestinal tract has been suggested as a mechanism underlying visceral hypersensitivity in conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). We aimed to study the potential therapeutic role of an in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmaceutics
Prif Awduron: Hanning, Nikita, De bruyn, Michelle, Ceuleers, Hannah, Boogaerts, Tim, Berg, Maya, Smet, Annemieke, De Schepper, Heiko U., Joossens, Jurgen, van Nuijs, Alexander L. N., De Man, Joris G., Augustyns, Koen, De Meester, Ingrid, De Winter, Benedicte Y.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229129/
https://ncbi.nlm.nih.gov/pubmed/34072320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060811
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