Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post‐inflammatory rat model for irritable bowel syndrome

BACKGROUND AND PURPOSE: Serine proteases have been re suggested as important mediators of visceral pain. We investigated their effect by using newly developed serine protease inhibitors with a well‐characterized inhibitory profile in a rat model of post‐inflammatory irritable bowel syndrome (IBS). E...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Ceuleers, Hannah, Hanning, Nikita, Heirbaut, Jelena, Van Remoortel, Samuel, Joossens, Jurgen, Van Der Veken, Pieter, Francque, Sven M, De bruyn, Michelle, Lambeir, Anne‐Marie, De Man, Joris G, Timmermans, Jean‐Pierre, Augustyns, Koen, De Meester, Ingrid, De Winter, Benedicte Y
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086981/
https://ncbi.nlm.nih.gov/pubmed/29911328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14396
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