Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold

[Image: see text] Fibroblast activation protein (FAP) is a serine protease that is generally accepted to play an important role in tumor growth and other diseases involving tissue remodeling. Currently there are no FAP inhibitors with reported selectivity toward both the closely related dipeptidyl p...

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Main Authors: Jansen, Koen, Heirbaut, Leen, Cheng, Jonathan D., Joossens, Jurgen, Ryabtsova, Oxana, Cos, Paul, Maes, Louis, Lambeir, Anne-Marie, De Meester, Ingrid, Augustyns, Koen, Van der Veken, Pieter
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2013
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027141/
https://ncbi.nlm.nih.gov/pubmed/24900696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300410d
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