Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold

[Image: see text] Fibroblast activation protein (FAP) is a serine protease that is generally accepted to play an important role in tumor growth and other diseases involving tissue remodeling. Currently there are no FAP inhibitors with reported selectivity toward both the closely related dipeptidyl p...

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Detalhes bibliográficos
Main Authors: Jansen, Koen, Heirbaut, Leen, Cheng, Jonathan D., Joossens, Jurgen, Ryabtsova, Oxana, Cos, Paul, Maes, Louis, Lambeir, Anne-Marie, De Meester, Ingrid, Augustyns, Koen, Van der Veken, Pieter
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027141/
https://ncbi.nlm.nih.gov/pubmed/24900696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300410d
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