Novel Small Molecule-Derived, Highly Selective Substrates for Fibroblast Activation Protein (FAP)

[Image: see text] Fibroblast activation protein (FAP) is a proline-selective serine protease. It is hardly expressed in healthy adult tissue but upregulated in tissue remodeling sites associated with several diseases including epithelial cancer types, atherosclerosis, arthritis and fibrosis. Ongoing...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: De Decker, An, Vliegen, Gwendolyn, Van Rompaey, Dries, Peeraer, Anke, Bracke, An, Verckist, Line, Jansen, Koen, Geiss-Friedlander, Ruth, Augustyns, Koen, De Winter, Hans, De Meester, Ingrid, Lambeir, Anne-Marie, Van der Veken, Pieter
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691567/
https://ncbi.nlm.nih.gov/pubmed/31413802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00191
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