Imaging of Fibroblast Activation Protein in Cancer Xenografts Using Novel (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine-Based Small Molecules

Fibroblast activation protein (FAP) has become a favored target for imaging and therapy of malignancy. We have synthesized and characterized two new (4-quinolinoyl)-glycyl-2-cyanopyrrolidine-based small molecules for imaging of FAP, QCP01 and [(111)In]QCP02, using optical and single-photon computed...

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Bibliografiske detaljer
Udgivet i:J Med Chem
Main Authors: Slania, Stephanie L., Das, Deepankar, Lisok, Ala, Du, Yong, Jiang, Zirui, Mease, Ronnie C., Rowe, Steven P., Nimmagadda, Sridhar, Yang, Xing, Pomper, Martin G.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214312/
https://ncbi.nlm.nih.gov/pubmed/33730493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c02171
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