Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7)

The presence of DPPII (dipeptidyl peptidase II; E.C. 3.4.14.2) has been demonstrated in various mammalian tissues. However, a profound molecular and catalytic characterization, including substrate selectivity, kinetics and pH-dependence, has not been conducted. In the present study, DPPII was purifi...

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Détails bibliographiques
Auteurs principaux: Maes, Marie-Berthe, Lambeir, Anne-Marie, Gilany, Kambiz, Senten, Kristel, Van der Veken, Pieter, Leiting, Barbara, Augustyns, Koen, Scharpé, Simon, De Meester, Ingrid
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2005
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134796/
https://ncbi.nlm.nih.gov/pubmed/15487984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041156
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