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T Cell Receptor Genotype and Ubash3a Determine Susceptibility to Rat Autoimmune Diabetes
Genetic analyses of human type 1 diabetes (T1D) have yet to reveal a complete pathophysiologic mechanism. Inbred rats with a high-risk class II major histocompatibility complex (MHC) haplotype (RT1B/D(u)) can illuminate such mechanisms. Using T1D-susceptible LEW.1WR1 rats that express RT1B/D(u) and...
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| Publicado no: | Genes (Basel) |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8227067/ https://ncbi.nlm.nih.gov/pubmed/34205929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060852 |
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