Carregant...

Autoantigen-Induced Focusing of Vβ13(+) T Cells Precedes Onset of Autoimmune Diabetes in the LEW.1WR1 Rat

The earliest events leading to autoimmune type 1 diabetes (T1D) are not known in any species. A T-cell receptor (TCR)-variable region, TCR-Vβ13, is required for susceptibility to autoimmune diabetes in rats, and selective depletion of Vβ13(+) T cells with an allele-specific monoclonal antibody preve...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Eberwine, Ryan A., Cort, Laura, Habib, Michael, Mordes, John P., Blankenhorn, Elizabeth P.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900547/
https://ncbi.nlm.nih.gov/pubmed/24150607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0462
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!