HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML

BACKGROUND: Leukaemia stem cells (LSCs) are responsible for the initiation, maintenance, and recurrence of acute myeloid leukaemia (AML), an aggressive haematological malignancy associated with drug resistance and relapse. Identifying therapeutic LSC targets is critical to curing AML. METHODS: Bioin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Li, Zheng, Wang, Fangce, Tian, Xiaoxue, Long, Jun, Ling, Bin, Zhang, Wenjun, Xu, Jun, Liang, Aibin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223385/
https://ncbi.nlm.nih.gov/pubmed/34167558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02007-4
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