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myc maintains embryonic stem cell pluripotency and self-renewal
While endogenous Myc (c-myc) and Mycn (N-myc) have been reported to be separately dispensable for murine embryonic stem cell (mESC) function, myc greatly enhances induced pluripotent stem (iPS) cell formation and overexpressed c-myc confers LIF-independence upon mESC. To address the role of myc gene...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916696/ https://ncbi.nlm.nih.gov/pubmed/20537458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2010.05.001 |
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