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Nucleostemin maintains self-renewal of embryonic stem cells and promotes reprogramming of somatic cells to pluripotency

Nucleostemin (NS) is a nucleolar GTP-binding protein that was first identified in neural stem cells, the functions of which remain poorly understood. Here, we report that NS is required for mouse embryogenesis to reach blastulation, maintenance of embryonic stem cell (ESC) self-renewal, and mammary...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Qu, Jian, Bishop, J. Michael
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373402/
https://ncbi.nlm.nih.gov/pubmed/22689653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103071
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