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HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML

BACKGROUND: Leukaemia stem cells (LSCs) are responsible for the initiation, maintenance, and recurrence of acute myeloid leukaemia (AML), an aggressive haematological malignancy associated with drug resistance and relapse. Identifying therapeutic LSC targets is critical to curing AML. METHODS: Bioin...

詳細記述

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書誌詳細
出版年:J Exp Clin Cancer Res
主要な著者: Li, Zheng, Wang, Fangce, Tian, Xiaoxue, Long, Jun, Ling, Bin, Zhang, Wenjun, Xu, Jun, Liang, Aibin
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223385/
https://ncbi.nlm.nih.gov/pubmed/34167558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02007-4
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