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Sp5 induces the expression of Nanog to maintain mouse embryonic stem cell self-renewal
Activation of signal transducer and activator of transcription 3 (STAT3) by leukemia inhibitory factor (LIF) maintains mouse embryonic stem cell (mESC) self-renewal. Our previous study showed that trans-acting transcription factor 5 (Sp5), an LIF/STAT3 downstream target, supports mESC self-renewal....
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5621696/ https://ncbi.nlm.nih.gov/pubmed/28961274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185714 |
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