Wnt/β-catenin and LIF–Stat3 signaling pathways converge on Sp5 to promote mouse embryonic stem cell self-renewal

Activation of leukemia inhibitor factor (LIF)–Stat3 or Wnt/β-catenin signaling promotes mouse embryonic stem cell (mESC) self-renewal. A myriad of downstream targets have been identified in the individual signal pathways, but their common targets remain largely elusive. In this study, we found that...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Ye, Shoudong, Zhang, Dongming, Cheng, Fei, Wilson, Daniel, Mackay, Jeffrey, He, Kan, Ban, Qian, Lv, Feng, Huang, Saifei, Liu, Dahai, Ying, Qi-Long
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732286/
https://ncbi.nlm.nih.gov/pubmed/26598557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.177675
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