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Sp5 induces the expression of Nanog to maintain mouse embryonic stem cell self-renewal

Activation of signal transducer and activator of transcription 3 (STAT3) by leukemia inhibitory factor (LIF) maintains mouse embryonic stem cell (mESC) self-renewal. Our previous study showed that trans-acting transcription factor 5 (Sp5), an LIF/STAT3 downstream target, supports mESC self-renewal....

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Tang, Ling, Wang, Manman, Liu, Dahai, Gong, Mengting, Ying, Qi-Long, Ye, Shoudong
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621696/
https://ncbi.nlm.nih.gov/pubmed/28961274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185714
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